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Grand Roundup

Grand Roundup: Top posts for the week of Sept. 14

The five most-read stories this week on Scope were:

So my life will be shorter than I’d hoped – what should I do differently?: In the latest installment of our Inspire patient series, a patient with “stage 4” Pancreatic Neuroendocrine Tumor discusses how his diagnosis has changed how he’s living his life.

Lloyd B. Minor, Stanford medical school’s dean, shares five principles of leadership: One of the highlights of the recent Medicine X conference was a course – “Navigating Complexity and Change: Principles of Leadership” – taught by our own leader, Lloyd B. Minor, MD.

Should we worry? Stanford’s global health chief weighs in on Ebola: In this piece, Michele Barry, MD, professor of medicine and director of Stanford’s Center for Innovation in Global Health, discusses the possibility of the Ebola epidemic spreading to the United States.

Stanford bioengineer develops a 50-cent paper microscopeManu Prakash, PhD, assistant professor of bioengineering, has developed an ultra-low-cost paper microscope to aid disease diagnosis in developing regions. The device is further described in a technical paper.

In a human brain, knowing a face and naming it are separate worries: Josef Parvizi, MD, PhD, associate professor of neurology, and Kalanit Grill-Spector, PhD, associate professor of psychology, have published new research on how our brains process face perception.

And still going strong – the most popular post from the past:

The mystery surrounding lung-transplant survival rates: A 2012 article in the San Francisco Chronicle offered a look at the challenges facing lung transplant patients and explored why a significant number don’t live beyond the five-year mark, despite improvements in survival rates.

Grand Roundup

Grand Roundup: Top posts for the week of Sept. 7

The five most-read stories this week on Scope were:

Skin cancer linked to UV-caused mutation in new oncogene, say Stanford researchers: Researchers here have identified a previously unknown oncogene that drives the development of a common human skin cancer in response to exposure to sunlight.

Proteins from pond scum revolutionize neuroscience: This entry focuses on the work of Stanford bioengineering professor Karl Deisseroth, MD, PhD, who just won the Keio Prize in Medicine,

What makes a good doctor – and can data help us find one?: At Medicine X last Saturday, ProPublica reporter Charles Ornstein posed to conference attendees an important question: How do you find a doctor? “This is trickier than you think,” he said and proceeded to discuss how data can yield helpful information for those looking for (or assessing their current) physician.

At Medicine X, four innovators talk teaching digital literacy and professionalism in medical school: One of the highlights of last weekend’s Medicine X was “Fostering Digital Citizenship in Medical School,” where four esteemed panelists talked about the innovative programs they’ve put in place at their institutions. The physician-speakers all believe that things like understanding social media and knowing how to build one’s digital footprint are crucial skills for doctors-to-be.

Stanford bioengineer develops a 50-cent paper microscopeManu Prakash, PhD, assistant professor of bioengineering, has developed an ultra-low-cost paper microscope to aid disease diagnosis in developing regions. The device is further described in a technical paper.

And still going strong – the most popular post from the past:

What are the consequences of sleep deprivation?: Brandon Peters, MD, an adjunct clinical faculty member at the Stanford Center for Sleep Sciences and Medicine, explains how lack of sleep can negatively affect a person’s well-being in this Huffington Post piece.

Grand Roundup

Grand Roundup: Top posts for the week of Aug. 31

Grand Roundup: Top posts for the week of Aug. 31

The five most-read stories this week on Scope were:

Breast cancer patients are getting more bilateral mastectomies – but not any survival benefit: The first-ever direct comparison of breast-cancer surgeries shows no survival benefit for women who had both breasts removed compared with women who underwent lumpectomy followed by radiation therapy. In this post, Christina Clarke, PhD, a research scientist and scientific communications advisor for the Cancer Prevention Institute of California, and a member of the Stanford Cancer Institute, discusses the findings and their implications for women.

Can Alzheimer’s damage to the brain be repaired?: Neuroscientist Frank Longo, MD, PhD, director of the Stanford Center for Memory Disorders, has pioneered the development of small-molecule drugs that might be able to restore nerve cells frayed by conditions such as Alzheimer’s disease.

When it comes to weight loss, maintaining a diet is more important than diet type: A meta-analysis of 48 studies on popular weight-loss programs found that if people stick to their diets (no matter the type) they lost weight, but ultimately the “weight-loss differences between individual diets were minimal and largely unimportant.”

Examining the effects of family time, screen time and parenting styles on child behavior: Results of The Learning Habit Study have shown that limiting screen time, increasing family time, and choosing parenting styles that rely on positive reinforcement are among the things that can help children perform better in school.

Stanford bioengineer develops a 50-cent paper microscopeManu Prakash, PhD, assistant professor of bioengineering, has developed an ultra-low-cost paper microscope to aid disease diagnosis in developing regions. The device is further described in a technical paper.

And still going strong – the most popular post from the past:

What are the consequences of sleep deprivation?: Brandon Peters, MD, an adjunct clinical faculty member at the Stanford Center for Sleep Sciences and Medicine, explains how lack of sleep can negatively affect a person’s well-being in this Huffington Post piece.

Grand Roundup

Grand Roundup: Top posts for the week of Aug. 24

The five most-read stories this week on Scope were:

“Sleep drunkenness” more prevalent than previously thought: A phenomenon known as “sleep drunkenness” may be more prevalent than previously thought, affecting as many as 1 in 7 adults, Stanford researchers report in a new study.

Our aging immune systems are still in business, but increasingly thrown out of balance: With advancing age, people grow increasingly vulnerable to infection, autoimmune disease and cancer. New research published in Proceedings of the National Academy of Sciences, suggests why that may come about.

New painkiller could tackle pain, without risk of addiction: A new pain-reliever may soon be on the scene that lacks the “high” of opioids and the cardiac-risk of non-steroidal anti-inflammatory (NSAIDs) drugs such as aspirin. A paper on the development was published this week in Science Translational Medicine.

Civilization and its dietary (dis)contents: Do modern diets starve our gut-microbial community?: In a review paper published last week in Cell Metabolism, Stanford married-microbiologist couple Justin Sonnenburg, PhD, and Erica Sonnenburg, PhD, warn that modern civilization and its dietary contents may be putting our microbial gut communities, and our health, at risk.

Biodesign fellows take on night terrors in children: Stanford’s Biodesign Program trains researchers, clinicians and engineers to be medical-technology innovators during its year-long fellowship. This piece highlights the work of several clinicians who have developed and are now testing a clinical method to treat night terrors in children.

And still going strong – the most popular post from the past:

What are the consequences of sleep deprivation?: Brandon Peters, MD, an adjunct clinical faculty member at the Stanford Center for Sleep Sciences and Medicine, explains how lack of sleep can negatively affect a person’s well-being in this Huffington Post piece.

Grand Roundup

Grand Roundup: Top posts for the week of July 27

The five most-read stories this week on Scope were:

Losing Jules: Breaking the silence around stillbirth: On the anniversary of her son’s death, a San Francisco mom writes a powerful piece on stillbirth. “I had no idea that in this age of medical advancement 1 in every 167 babies in the United States is stillborn,” writes Polly Styker. “Just over half a percent (.6 percent) doesn’t sound like a lot – until it’s you.”

How to get a student-friendly room for under $100: In the latest installment of SMS Unplugged, medical student Natalia Birgisson shows incoming students how to set up their room for under $100.

The woman in the elevator: dealing with death in medical training: In a recent SMS Unplugged entry, medical student Jennifer DeCoste-Lopez shares her insight on dealing with death and loss in medical training.

Stanford partnering with Google [x] and Duke to better understand the human body: Researchers at Stanford, in collaboration with Duke University and Google [x], are planning a comprehensive initiative to understand the molecular markers that are key to health and the changes in those biomarkers that may lead to disease. The project was featured in a Wall Street Journal article last week.

Induced pluripotent stem cell mysteries explored by Stanford researchers: Stanford researchers answer fundamental questions about the use of using pluripotent stem cells in a clinical setting in two new papers in the Journal of the American College of Cardiology. The work was led by Stanford cardiologist Joseph Wu, MD, PhD, director of the Stanford Cardiovascular Institute.

And still going strong – the most popular post from the past:

Researchers explain how “cooling glove” can improve exercise recovery and performance: The “cooling glove,” a device that helps people cool themselves quickly by using their hand to dissipate heat, was created more than a decade ago by Stanford biologists Dennis Grahn and Craig Heller, PhD. This video demonstrates the device and explains how it can be used to dramatically improve exercise recovery and performance.

Grand Roundup

Grand Roundup: Top posts for the week of July 20

The five most-read stories this week on Scope were:

What other cultures can teach us about managing postpartum sleep deprivation: A recent Huffington Post piece from the Stanford Center for Sleep Sciences and Medicine examined how mothers in other countries cope with postpartum sleep deprivation.

Stanford bioengineer develops a 50-cent paper microscopeManu Prakash, PhD, assistant professor of bioengineering, has developed an ultra-low-cost paper microscope to aid disease diagnosis in developing regions. The device is further described in a technical paper.

How much caffeine is really in one cup of coffee?: As described in a Scientific American piece, new research shows the caffeine and caffeoylquinic acid content can vary greatly depending on the type and preparation of coffee.

Why sleeping in on the weekends may not be beneficial to your health: This blog entry links to a Wired Science article describing the dangers of oversleeping.

In medicine, showing empathy isn’t enough: In the latest installment of our SMS Unplugged series, medical student Moises Gallegos discusses some of the things he’s learned and observed about health disparities.

And still going strong – the most popular post from the past:

The mystery surrounding lung-transplant survival rates: A 2012 article in the San Francisco Chronicle offered a look at the challenges facing lung transplant patients and explored why a significant number don’t live beyond the five-year mark, despite improvements in survival rates.

Grand Roundup

Grand Roundup: Top posts for the week of July 13

The five most-read stories this week on Scope were:

“As a young lung cancer patient, I had to find my own path”: Fighting stage IV with full forceInspire contributor Emily Bennett Taylor, a Stage IV lung cancer survivor and spokesperson/patient advocate, discusses her choice to pursue aggressive treatment following diagnosis at age 28.

The woman in the elevator: dealing with death in medical training: In the latest installment of SMS Unplugged, medical student Jennifer DeCoste-Lopez shares her insight on dealing with death and loss in medical training.

Mourning the loss of AIDS researcher Joep Lange: Stanford researchers specializing in HIV/AIDS are among those around the world mourning the loss of Dutch scientist Joep Lange, MD, PhD, a leading AIDS researcher who died in the recent Malaysian Airlines crash in Ukraine.

Stanford bioengineer develops a 50-cent paper microscopeManu Prakash, PhD, assistant professor of bioengineering, has developed an ultra-low-cost paper microscope to aid disease diagnosis in developing regions. The device is further described in a technical paper.

Stanford team develops nanotech-based microchip to diagnose Type 1 diabetes: Researchers here, including pediatric endocrinologist Brian Feldman, MD, PhD, have invented a cheap, portable, microchip-based test for diagnosing type-1 diabetes. The test could speed up diagnosis and enable studies of how the disease develops.

And still going strong – the most popular post from the past:

Researchers explain how “cooling glove” can improve exercise recovery and performance: The “cooling glove,” a device that helps people cool themselves quickly by using their hand to dissipate heat, was created more than a decade ago by Stanford biologists Dennis Grahn and Craig Heller, PhD. This video demonstrates the device and explains how it can be used to dramatically improve exercise recovery and performance.

Grand Roundup

Grand Roundup: Top posts for the week of July 6

The five most-read stories this week on Scope were:

It’s time for innovation in how we pay for medical schoolJoanne Conroy, MD, chief executive officer of Lahey Clinic & Medical Center in Burlington, Mass., discusses options to decrease undergraduate medical school debt. This post originally appeared on Wing of Zock.

Without exercise, Americans are growing more obese, according to Stanford researchers: Inactivity rather than overeating could be driving the surge in Americans’ obesity, according to a study by Stanford researchers that includes first author Uri Ladabaum, MD.

The behavioral consequences of overindulgence: Researchers from the Stanford Graduate School of Business have conducted a series of experiments on how overindulgence affects our pleasure in food. Their findings offer insights for both individuals that have trouble eating and drinking in moderation and those who are picky eaters.

Fewer than six degrees of separation: the small world of higher education: In this entry of the SMS Unplugged series, med student Hamsika Chandrasekar discusses the need to address diversity of undergraduate institutions in medical school.

Stanford patient on having her genome sequenced: “This is the right thing to do for our family”: Patient Julie Prillinger’s genome was among the first to be sequenced through a pilot program of the new Clinical Genomics Service at Stanford Hospital & Clinics. The pilot phase of the service is limited to specific patient groups.

And still going strong – the most popular post from the past:

The mystery surrounding lung-transplant survival rates: A 2012 article in the San Francisco Chronicle offered a look at the challenges facing lung transplant patients and explored why a significant number don’t live beyond the five-year mark, despite improvements in survival rates.

Ask Stanford Med, Chronic Disease, Grand Roundup, Stanford News

Stanford physician Sanjay Basu on using data to prevent chronic disease in the developing world

Stanford physician Sanjay Basu on using data to prevent chronic disease in the developing world

Basu and RosenkranzThere’s a new health policy challenge in developing countries. Though many see chronic conditions like type-2 diabetes and heart disease as problems plaguing the wealthiest nations, “Nearly 80 percent of the deaths worldwide from these two diseases are coming from the developing world,” says Sanjay Basu, MD, PhD, an assistant professor of medicine at the Stanford Prevention Research Center.

But Basu is working to change this statistic, and his efforts just won him the $100,000 George Rosenkranz Prize for Health Care Research in Developing Countries. Administered by Stanford’s Center for Health Policy/Center for Primary Care and Outcomes Research at the Freeman Spogli Institute for International Studies, the award will help fund Basu’s large-scale data collection project in India. With a data set from over 65,000 people, Basu hopes to improve type-2 diabetes screening in the country, leading to better treatment and detection of the disease.

A researcher focused primarily on global development and human health, Basu is also an internal medicine physician with a master’s in medical anthropology and a doctorate in epidemiology. In the following Q&A, he discusses his current research interests and plans for the future.

How did you first become interested in global health policy and the developing world?

As a child, our family went back and forth between the United States and India, and the contrasts in daily life were striking and overwhelming. There is a sense in many parts of India that life is a privilege, and a constant struggle to maintain.

Your research in India will involve data collection and mathematical modeling, which sounds rather abstract. How does this work translate into real-world improvements in people’s health?

Our research serves as a bridge between the clinical science of how to prevent and treat disease, and the detailed operations of how to actually deliver better prevention and treatment in the real world. What we specifically do is combine biological and clinical data with data on program reach, budgets, and operations. In other words, we might learn how to build a car in a textbook, but our models look at how to make the car factory operate optimally so that the product, in the end, is drivable. We’ve worked closely with both government agencies and non-governmental groups to deliver programs in real-world populations, and to continuously improve those programs over time. For example, our work on how to introduce better tobacco control programs in India has actually resulted in recent legislation that has lowered tobacco use in some critical parts of the population.

What’s different about approaching chronic disease prevention in India versus in the United States?

The sheer size and diversity of the population is one big difference. India is four times the size of the United States, and far more diverse. There is simultaneously malnutrition and obesity, starvation and type-2 diabetes, vitamin deficiency and heart attacks – often in the same city. That means designing programs for a country – or a province, or even a city – requires a lot of attention to complicated perverse outcomes that may happen. For example, we’ve looked into reducing sodium intake as a strategy to lower hypertension and cardiovascular disease. But we also have to make sure that we don’t generate iodine deficiency since salt is the major delivery strategy for iodine and, unlike the United States, iodine deficiency is a serious concern in India.

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Grand Roundup

Grand Roundup: Top posts for the week of June 22

The five most-read stories this week on Scope were:

Empowered is as empowered does: Making a choice about living with lupus: Inspire contributor Pattie Brynn Hultquist writes about her experience living with the autoimmune disease systemic lupus erythematosus and how she became an empowered patient.

Stanford bioengineer develops a 50-cent paper microscopeManu Prakash, PhD, assistant professor of bioengineering, has developed an ultra-low-cost paper microscope to aid disease diagnosis in developing regions. The device is further described in a technical paper.

Student transitions in medicine: putting blinders on: In the latest installment of SMS Unplugged, medical student Moises Gallegos discusses the importance of mentorship and support during medical school transitions.

Talk from the hand: the role of gesture in verbal communication: An Italian study found that the sight of gestures combined with the sound of speech created a whole-body system of communication in which movement played an important role in helping listeners understand language that was unclear.

Secrets of fat cells discoveredMary Teruel, PhD, and colleagues have studied the life cycle of fat cells and what findings could mean for the treatment of obesity and diabetes.

And still going strong – the most popular post from the past:

The mystery surrounding lung-transplant survival rates: A 2012 article in the San Francisco Chronicle offered a look at the challenges facing lung transplant patients and explored why a significant number don’t live beyond the five-year mark, despite improvements in survival rates.

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