Earlier this week, fellow Scope contributor Bruce Goldman reported on a paradigm-shifting process developed by Stanford psychiatrist and bioengineer Karl Deisseroth, MD, PhD, and colleagues. Using the process, called CLARITY, scientists were able to turn a mouse brain into an "optically transparent, histochemically permeable replica of itself."
CLARITY is powerful. It will enable researchers to study neurological diseases and disorders, focusing on diseased or damaged structures without losing a global perspective. That’s something we’ve never before been able to do in three dimensions.
This haunting image depicts a three-dimensional rendering of clarified brain imaged from the ventral half. To fully experience the new method’s awe-inspiring capabilities, watch this fly-through video.
Previously: Scientific community (and Twitter) buzzing over Stanford’s see-through brain, Lightning strikes twice: Optogenetics pioneer Karl Deisseroth’s newest technique renders tissues transparent, yet structurally intact and Peering deeply – and quite literally – into
Photo by Deisseroth lab