Earlier this week, fellow Scope contributor Bruce Goldman reported on a paradigm-shifting process developed by Stanford psychiatrist and bioengineer Karl Deisseroth, MD, PhD, and colleagues. Using the process, called CLARITY, scientists were able to turn a mouse brain into an "optically transparent, histochemically permeable replica of itself."
National Institutes of Health Director Francis Collins, MD, PhD, commented on the breakthrough in a recent blog post, saying:
CLARITY is powerful. It will enable researchers to study neurological diseases and disorders, focusing on diseased or damaged structures without losing a global perspective. That’s something we’ve never before been able to do in three dimensions.
This haunting image depicts a three-dimensional rendering of clarified brain imaged from the ventral half. To fully experience the new method’s awe-inspiring capabilities, watch this fly-through video.
Previously: Scientific community (and Twitter) buzzing over Stanford’s see-through brain, Lightning strikes twice: Optogenetics pioneer Karl Deisseroth’s newest technique renders tissues transparent, yet structurally intact and Peering deeply – and quite literally – into
Photo by Deisseroth lab
