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Stanford team cracks key immune protein’s crystal structure, separating its yin from its yang

A team led by Stanford structural biologist Chris Garcia, PhD, has revealed the crystal structure of a protein complex centered around one of the body's most important immune signaling proteins:...

The med student and the machine

...double-speed, taught immunology to my first-year peers, and entered the hospital for an afternoon of clinical practice. I got home, studied more, went to see some friends, and didn't tell...

An honest answer to the question “How’s medical school?”

...our lecture on immunology. This patient recounted his experiences of being ignored by doctors who don’t understand what it’s like to live life like “the Bubble Boy.” Next, with rumbling...

Transplanting mismatched organs may be possible — and safe — in the future, new findings suggest

For those hoping for a new heart, liver, bone marrow or other organ, the wait for a compatible organ has always been part of the excruciating drama of transplantation. If...

Rheumatoid arthritis may be triggered by a missing molecular “anchor,” but new research suggests a fix

In a study published in Nature Immunology, Stanford rheumatologist Connie Weyand, MD, PhD, and her colleagues have dug up a defect thought to lead to rheumatoid arthritis. It seems this...

When will dengue turn life-threatening? Researchers identify genes that provide a tell

...and of microbiology and immunology, have reanalyzed previously-published dengue patient data, discovering a key set of genes whose expression can predict who will suffer severe dengue. As explained by our...

Positive mindset helps with an allergy therapy’s side effects, says Stanford study

...if they could help patients reframe their view of the treatment's side effects to lower their anxiety. Their findings appear today in the Journal of Allergy and Clinical Immunology: In...

Blood test may detect early signs of lung-transplant rejection

After receiving a lung transplant, patients face the likely chance that their body’s immune system will reject the transplanted organ. Rejection can happen at any time due to a variety...

Immunotherapy target identified for pediatric cancers

When the FDA announced in 2017 that it was approving an immunotherapy treatment for children with certain relapsed blood cancers, doctors and patients were pretty excited. That treatment, tisagenlecleucel (brand...

Mistaken identity: Influenza/narcolepsy autoimmunity link confirmed

There's a theory in immunology, called the molecular mimicry hypothesis, that autoimmunity (where the immune system turns on the body's own tissues) is the result of mistaken identity: The immune...

In the Spotlight: “Science is like meditation”

...and immunology. When we talked, he shared his experiences in science, and reflected on how he remains positive and grounded in day-to-day life. Here's a closer look: When you came...

Can flicking a molecular switch restore the aging immune system’s competence?

The aphorism "with age comes wisdom" is mostly true. But a new study in Cell Reports by Stanford immunologists Jorg Goronzy, MD, Connie Weyand, MD, and their colleagues here and...

The future of FAST: Bright and bigger

...and immunology and a chief program officer of FAST. This fall, FAST added a second high school, James Lick High School, also part of the East Side Union High School...

Amazing, awesome, meaningful and life-changing: FAST students, leaders and mentors reflect

...graduate student in immunology, told me. "It sounds really intimidating having to spend 13 or 14 Saturdays of your year at the high school. During the week you're stressed and...

FAST in action: A visit to Andrew P. Hill High School

...a Stanford graduate student in immunology, described. The guidance, Andrew Hill students told me, is welcome. "First-generation parents are motivating their kids to go to college, but we don't really...

A look at how colds and chronic disease affect DNA expression

We’re all born with a DNA sequence that encodes (in the form of genes) the very traits that make us, us — eye color, height, and even personality. We think...