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How to hack a cell: Protein bubbles

In this amazing video, Tom Kirchhausen, PhD, a Harvard Medical School professor of cell biology, shows how tiny protein-bubbles form to carry cargo, such as nutrients and hormones, across cell membranes. Using Total Internal Reflection Fluorescence microscopy (TIRF), researchers were able to capture, for the first time, real-time footage of how this crucial cellular mechanism happens, providing new insights on how drugs might interact with life’s moving parts at the molecular level.

These findings were published in the August 3 issue of Cell.

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